Blood stasis (BS) is characterized as a disorder of blood circulation. In traditional Korean medicine (TKM), it is viewed as a cause\nfactor of diseases such as multiple sclerosis and stroke. This study investigated differences in the plasma metabolites profiles of\nsubjects displaying BS or non-BS patterns. Thirty-one patients with cerebral infarction diagnosed with BS and an equal number\nof sex- and age-matched non-BS patients were enrolled. Metabolic profiling was performed using UPLC-MS. The ratio of subjects\nwith a rough pulse and purple coloration of the tongue was higher in patients presenting with BS pattern. Through metabolomics\nanalysis, 82 metabolites that differed significantly between the BS and non-BS pattern were identified, and the two groups were\nsignificantly separated using an orthogonal partial least square-discriminant analysis model (
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